Former Lab Members

Trade-offs between endurance running and power production in deer mice

Somo, D.A., Marangozis, S.C., Cumming, M.L.L., McClelland, G.B., and Scott, G.R. (2026) Evolved increases in running performance in cold hypoxia in high-altitude deer mice. J. Exp. Biol. 229, jeb252284.

Whole animal performance differences in grip strength reflected in forelimb muscle metabolic profiles of deer mice

Beiging of white adipose tissue with cold exposure in highland deer mice

Cardiac monocarboxylate transporter expression in deer mice

Post-exercise recovery of liver glycogen in low and highland deer mice

​

Dessureault, L.M., Tod, R.A., and McClelland, G.B. (2024). Metabolic recovery from submaximal exercise in hypoxia acclimated high altitude deer mice (Peromyscus maniculatus). Comp. Biochem. Physiol. B. 274: 111004

Interactive effects of cold and short day in brown adipose tissue

The effect of cold hypoxia acclimation on liver mitochondria respiration as an important mechanism to support thermogenesis in highland deer mice

​Evolution of serum albumin for fatty acid transport in highland taxa

Plasticity of thermoneutral zones with cold acclimation in deer mice

Plasticity of brown adipose tissue to cold and hypoxia in high altitude deer mice

Ontogeny and plasticity of calcium handling in high altitude deer mice

Ontogeny of skeletal muscle fiber-type in high and low altitude deer mice

Mitochondrial metabolism of brown adipose tissue from low and high-altitude deer mice

The effects of cold adaptation on the developmental regulation of Sarcolipin in deer mice

Energetics of copper exposed killifish

Kulesza, A., Leonard, E.M., and McClelland, G.B. (2020) Influence of 96h sub-lethal copper exposure on aerobic scope and recovery from exhaustive exercise in killifish (Fundulus heteroclitus). Aquatic Toxicology. 218:105373

Stimulation of respiration in Cu-exposed killifish (Fundulus heteroclitus)​

Oxygen-dependent gene and protein expression under copper, hypoxia and combined copper and hypoxia exposure in the common Killifish, Fundulus Heteroclitus

Muscle Metabolism with Exercise in High and Low Altitude Deer Mice (Peromyscus maniculatus)

The effects of acute hypoxia and copper exposure on gill morphometry and gene expression in the common killifish

Changes in the machinery associated with aerobic metabolism in response to exercise in trout

Acclimation of mice to hypoxia: inducing the lactate paradox

Effect of dietary iron on water-borne Cu toxicity in zebrafish

​

Craig, P.M., Galus, M., Wood, C.M., and McClelland, G.B. (2009) Dietary iron alters waterborne-copper induced gene expression in softwater acclimated zebrafish (Danio rerio). Am. J. Physiol. 296:R362-R373.​

The effects of aquatic-to-aerial transition on gill morphology and blood metabolite levels in the plainfin midshipman

Differences in plasma and muscle lipids between high and low aerobic capacity rats

Spacial muscle remodelling in zebrafish

​

Le Moine, C.M.R., Craig, P.M., Dhekney, K., Kim, J.J., and McClelland, G.B. (2010) Temporal and spatial patterns of gene expression in skeletal muscles in response to swim training in adult zebrafish (Danio rerio). J. Comp. Physiol. B. 180(1):151-60.

McClelland, G.B., Craig, P.M., Dhekney, K and Dipardo, S. (2006) Temperature- and exercise-induced gene expression and metabolic enzyme changes in skeletal muscle of adult zebrafish (Danio rerio). J. Physiol. (London), 577(2):739-751.​

Modelling Ucrit in fish

Exercise- and Cold-induced muscle remodelling in zebrafish

​

McClelland, G.B., Craig, P.M., Dhekney, K and Dipardo, S. (2006) Temperature- and exercise-induced gene expression and metabolic enzyme changes in skeletal muscle of adult zebrafish (Danio rerio). J. Physiol. (London), 577(2):739-751.​

Is thermal tolerance a driver in the range expansion of an invasive fish?

The role of peptide hormones in glucose handling in high altitude deer mice

Flexibility in thermogenic capacity with photoperiod and temperature

Ontogeny of mitochondrial fuel use in deer mice

Kinetics of muscle CPT1 in low and highland deer mice

Regulation of mitochondrial respiration and non-shivering thermogenesis in brown adipocytes

Muscle fiber specific lipid use during shivering thermogenesis in deer mice

Regulation of pyruvate dehydrogenase with exercise in highland deer mice

​

Coulson, S.Z., Lyons, S.A., Robertson, C.E., Fabello, B., Dessureault, L.M., and McClelland, G.B. (2024) Regulation of muscle pyruvate dehydrogenase activity and exercise fuel use in high-altitude deer mice. J. Exp. Biol. 227(16):jeb246890

The liver as a hub for thermogenesis and exercise at high altitude

Skeletal muscle phenotypes for locomotion and thermogenesis

​

Garrett, E.J., Prasad, S.K., Schweizer, R.M., McClelland, G.B., and Scott, G.R. (2024) Evolved changes in phenotype across skeletal muscles in deer mice native to high altitude. Am. J. Physiol. 326(4):R277-R332.

Changes in thermal conductance with cold acclimation in deer mice

Hayward, L, Robertson, C.E., and McClelland, G.B. (2022) Phenotypic plasticity to chronic cold exposure in two species of Peromyscus from different environments. J. Comp. Physiol. B. https://doi.org/10.1007/s00360-021-01423-4

Ontogeny of brown adipose tissue of high and low altitude deer mice

Ontogeny of shivering thermogenesis of low and high-altitude deer mice

Membrane transport limitations for lipid metabolism in highland deer mice

Brown adipose tissue plasticity with cold and hypoxia acclimation in deer mice

Effect of cold acclimation on locomotory metabolism in high altitude deer mice (Peromyscus maniculatus)

Effect Of Hypoxia Acclimation On The Fuel Use Patterns Of Highland Deer Mice (Peromyscus maniculatus) During Exercise

​

Lau, D., Mahalingam, S., Connaty, A.D., Wall, N., Cheviron, Z.A., Storz, J.F., Scott, G.R., and McClelland, G.B. (2017) Acclimation to hypoxia increases carbohydrate use during exercise in high-altitude deer mice. Am. J. Physiol, Am. J. Physiol. 312: R400–R411.​

The Effects of Contamination in Hamilton Harbour on Swimming Performance and Liver Glycogen Content in Round Gobies

Muscle signalling with exercise intensity

Regulatory Mechanism of Fat Metabolism in Migratory Spawning Sockeye Salmon: Expression of PPARa in Red Muscle Tissue

​

Morash, A.J., Le Moine, C.M.R., Yu, W., Hill, J. A., Patterson, D.A., Farrell, A.P., and McClelland, G.B. Genomic and metabolic preparation in sockeye salmon (Oncorhynchus nerka) for spawning migration. Physiol. Biochem. Zool.​

Exercise induced remodelling of skeletal muscle in adult zebrafish

​

Le Moine, C.M.R., Craig, P.M., Dhekney, K., Kim, J.J., and McClelland, G.B. (2010) Temporal and spatial patterns of gene expression in skeletal muscles in response to swim training in adult zebrafish (Danio rerio). J. Comp. Physiol. B. 180(1):151-60.​

Genetic and enzymatic changes in mitochondrial fat oxidation in muscle of sockeye salmon through the course of migration

Divalent metal transporter expression in Cu exposed zebrafish​

Exercise fuel use in rats selectively bred for running capacity​

Changes in Honeybee muscle proteome with foraging experience

​

Schippers, M.-P., Dukas, R., Smith, R.W., Wang, J., Smolen, K. and McClelland, G.B. (2006) Lifetime performance in foraging honey bees: behaviour and physiology J. Exp. Biol. 209: 3828-3836.​

CPTI gene expression in trout